Plasma Lipoproteins, Part B: Volume 129 : Characterization, Cell Biology, and Metabolism
Plasma Lipoproteins, Part B: Volume 129 : Characterization, Cell Biology, and Metabolism Nathan P. Colowick
Author: Nathan P. Colowick
Date: 13 Jun 1986
Publisher: Elsevier Science Publishing Co Inc
Original Languages: English
Book Format: Hardback::960 pages
ISBN10: 0121820297
ISBN13: 9780121820299
Publication City/Country: San Diego, United States
Dimension: 152x 229mm::1,400g
Download: Plasma Lipoproteins, Part B: Volume 129 : Characterization, Cell Biology, and Metabolism
==========================๑۩๑==========================
Download PDF, EPUB, MOBI Plasma Lipoproteins, Part B: Volume 129 : Characterization, Cell Biology, and Metabolism. Since its initial discovery in 1929 Michel Macheboeuf (), high-density lipoprotein (HDL) has been an intriguing macromolecular assembly of proteins and lipids offering constant excitement and surprises to the biomedical community.In recent decades, HDL attracted a lot of attention mainly because of its important role in atheroprotection. However, more recent findings propose a Triglycerides represent 1 component of a heterogeneous pool of triglyceride-rich lipoproteins (TGRLs). The reliance on triglycerides or TGRLs as cardiovascular disease (CVD) risk biomarkers prompted investigations into therapies that lower plasma triglycerides as a means to reduce CVD events. Genetic studies identified TGRL components and pathways involved in their synthesis and metabolism. We Review Article Lipids, Lipoproteins, and Age-Related Macular Degeneration Katayoon B. Ebrahimi and James T. Handa Retina Division, Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA Correspondence should be addressed to James T. Handa, [email protected] Received 2 February 2011; Revised 14 April 2011; Accepted 9 Metabolism and Modification of Apolipoprotein B-Containing Lipoproteins Involved in Dyslipidemia and Atherosclerosis ApoC-III delays the metabolism of TG-rich lipoproteins inhibiting LPL activity and apoE-dependent hepatic uptake, lipid-free apoB is considered to induce cell death disturbance of the plasma membrane. The high Get this from a library! Plasma lipoproteins. Part B, Characterization, cell biology, and metabolism. [John J Albers; Jere P Segrest;] - The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, 155 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know. Plasma Lipoproteins, Part B: Characterization, Cell Biology, and Metabolism: 129: Nathan P. Colowick, Nathan P. Kaplan, John J. Albers, Jere P. Segrest lipoprotein lipase (LPL) plays a major role in the metabolism and transport of lipids. It is the enzyme responsible for the hydrolysis of core triglycerides (TGs) in chylomicrons and very low-density lipoproteins (VLDLs), producing chylomicron remnants and intermediate-density lipoproteins (IDLs), respectively (54, 86).Besides its hydrolytic activity, LPL can interact with lipoproteins to Levels of certain plasma lipids and lipoproteins are key risk factors for cardiovascular disease (CVD). The search for the genetic contributors to variation in plasma lipid and lipoprotein levels The high-density lipoproteins (HDL) are the smallest and densest of the plasma lipoproteins and are approximately one half protein and one half lipid weight. The principal protein constituent of HDL is apolipoprotein A1 (APOA1) followed APOA2; minor protein components are APOA4, APOD, APOE, APOF, APOH, APOJ and APOM. Napoli C, D’Armiento FP, Mancini FP, et al. Fatty streak formation occurs in human fetal aortas and is greatly enhanced maternal hypercholesterolemia.Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions. Increased Endosomal Cholesteryl Ester Hydrolysis in the Presence of Plasma Membrane—In previous studies with cultured cells it has been estimated that about 70% of cholesterol produced endosomal hydrolysis of cholesteryl ester is transferred to the plasma membrane (28, 29). Using our cell-free system we asked, therefore, whether the Cultures of stem cells from discarded sources supplemented with dexamethasone, a synthetic glucocorticoid receptor agonist, generate cultured red blood cells (cRBCs) in numbers sufficient for transfusion. According to the literature, however, erythroblasts generated with dexamethasone exhibit low enucleation rates giving rise to cRBCs that survive poorly in vivo. The knowledge that the Purchase Plasma Lipoproteins, Part B, Volume 129 - 1st Edition. Print Book & E-Book. ISBN 9780121820299, 9780080882468 Volume 129 1st Edition Characterization, Cell Biology, and Metabolism. Editor-in-Chiefs: Nathan Colowick Nathan Kaplan. Amazon配送商品ならPlasma Lipoproteins, Part B, Volume 129: Characterization, Cell Biology, and Metabolism (Methods in Enzymology)が通常配送無料。更にAmazonならポイント還元本が多数。Nathan P. Colowick, Nathan P. Kaplan, John J. Albers, Jere P. Segrest作品ほか、お急ぎ便対象商品は当日お届けも可能。 Biology of Sex Differences volume 10, Article number: A sex-dependent regulation of Pemt in the regulation of plasma high-density lipoproteins and VLDL has been demonstrated in mice,which are part of the lipid metabolism. In obesity, DNL capacity of adipocytes is substantially reduced and this may contribute to the associated The hydrophobic lipid components of lipoproteins, cholesteryl ester and triglyceride, are transferred between all lipoproteins a specific plasma glycoprotein, termed lipid transfer protein (LTP). LTP facilitates lipid transfer an exchange process in which cholesteryl ester and … A model of plasma apoC-III metabolism (Fig. 2) was developed using Simulation which equals the plasma concentration multiplied plasma volume; plasma volume was estimated as 4.5% of body weight. Further evidence for the presence of non-equilibrating pools of apolipoproteins C-II and C-III in plasma lipoproteins. J. Lipid Res. 34: 1793 CETP is a plasma protein that modulates atherosclerosis risk through its HDL-cholesterol reducing action. The aim of this work was to examine the effect of the PPARα agonist, ciprofibrate, on the CETP gene expression, in the presence and absence of apolipoprotein (apo) CIII induced hypertriglyceridemia, and its impact on the HDL metabolism. Monoclonal antibodies to human plasma low-density lipoproteins. II. Evaluation for use in radioimmunoassay for apolipoprotein B in patients with coronary artery disease Atherosclerosis and its sequelae, such as myocardial infarction and stroke, are the leading cause of death worldwide. Vascular endothelial cells (EC) play a critical role in vascular homeostasis and disease. Atherosclerosis as well as its independent risk factors including diabetes, obesity, and aging, are hallmarked endothelial activation and dysfunction. Metabolic pathways have emerged as Read "Structural models of human apolipoprotein A-I, Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. ABCG1 is often visually depicted at the cell surface, Since vitamin E, lutein and zeaxanthin are exclusively obtained from the diet and transported plasma lipoproteins, pathways involved in their intestinal absorption are of major importance. Rader, D.J. Spotlight on HDL biology: New insights in metabolism, function, and translation Also, similar to GSI-treated mice, fractionation of plasma lipoproteins density gradient ultracentrifugation or size-exclusion fast protein liquid chromatography showed reduced TGs in VLDL and LDL fractions in L-Ncst mice (data not shown; Figure 2E) and no change in VLDL-TG secretion (Figure 2F) but did show a marked reduction in appearance Plasma Lipoproteins Part B Characterization, Cell Biology, and Metabolism John J. Albers Jere P. Segrest. CONTRIBUTORS TO VOLUME 129 ix PREFACE X V VOLUMES IN SERIES XVii Section I. Characterization of Plasma Lipoproteins 1. Zonal Ultracentrifugation JOSEF R. PATSCH AND 1 Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA. 2 Magdalen College, Oxford University, Oxford, United Get a full overview of Methods in Enzymology Book Series. Most recent Volume: Enzyme Engineering and Evolution, Including Directed Evolution Plasma lipoproteins, part B. Characterization, cell biology, and metabolism. Academic Press, New York, pp 716–719 Google Scholar Fraley DS, Adler S (1976) Isohydric regulation of plasma potassium bicarbonate in the rat. Liposomes are cellular structures made up of lipid molecules. Important as a cellular model in the study of basic biology, liposomes are also used in clinical applications such as drug delivery and virus studies. * Liposomes in Biochemistry* Liposomes in Molecular Cell Biology* Liposomes in Molecular Virology Atherosclerosis is a major complication of diabetes. The dyslipidaemia of diabetes appears to play an important part in the atherosclerotic process mainly through the disturbance in triglyceride metabolism and the resulting low HDL cholesterol. The article discusses abnormalities in fat metabolism as observed in both chylomicron oin the intestine and very low density lipoprotein (VLDL) in the
Download Plasma Lipoproteins, Part B: Volume 129 : Characterization, Cell Biology, and Metabolism